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Advanced solid malignancy,PIK3CA mutated,AKT1 mutated, PTEN mutation, PTEN alteration, metastatic,ER ,breast,ovarian,endometrial,AZD5363,AKT inhibitor,

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Advanced Solid Malignancy, Safety and Tolerability, Pharmacokinetics Trial in Worldwide (AZD5363)

Active, not recruiting
  • Advanced Solid Malignancy
  • +13 more
  • Los Angeles, California
  • +33 more
Dec 22, 2022

Estrogen Receptor Positive Breast Cancer Trial in United Kingdom (AZD5363, Placebo, Fulvestrant)

Active, not recruiting
  • Estrogen Receptor Positive Breast Cancer
  • Manchester, Greater Manchester, United Kingdom
  • +20 more
Aug 5, 2022

Solid Tumor, ARID1A Gene Mutation Trial in Greenville (Tazemetostat)

Suspended
  • Solid Tumor
  • ARID1A Gene Mutation
  • Greenville, South Carolina
    Prisma Health Cancer Institute
Jan 10, 2023

Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer Trial (MEN1611, Eribulin)

Not yet recruiting
  • Breast Cancer
  • +2 more
  • (no location specified)
Apr 12, 2023

Advanced or Metastatic Breast Cancer, ER+ve Advanced or Metastatic Breast Cancer Trial in Worldwide (AZD5363 when combined with

Completed
Has Results
  • Advanced or Metastatic Breast Cancer
  • ER+ve Advanced or Metastatic Breast Cancer
  • AZD5363 when combined with weekly paclitaxel.
  • +2 more
  • Plovdiv, Bulgaria
  • +40 more
Dec 23, 2022

Advanced Breast Cancer Trial in Lebanon (Fulvestrant, Neratinib, Alpelisib)

Not yet recruiting
  • Advanced Breast Cancer
  • Lebanon, New Hampshire
    Dartmouth Hitchcock Medical Center
Jun 28, 2023

Advanced Malignant Solid Tumor, Metastatic Malignant Solid Tumor, Refractory Malignant Solid Tumor Trial in Canada, United

Recruiting
  • Advanced Malignant Solid Neoplasm
  • +2 more
  • Biopsy
  • +6 more
  • Boston, Massachusetts
  • +5 more
Jan 7, 2023

HER2-positive Breast Cancer Trial in Rome (PIK3CA analysis)

Active, not recruiting
  • HER2-positive Breast Cancer
  • PIK3CA analysis
  • Rome, RM, Italy
    Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Feb 20, 2023

Cancer, Solid Tumors Trial in United States (Vevorisertib, Fulvestrant, Paclitaxel)

Terminated
Has Results
  • Cancer
  • Solid Tumors
  • Las Vegas, Nevada
  • +5 more
Jun 14, 2022

Anatomic Stage IV Breast Cancer AJCC v8, HER2-Positive Breast Carcinoma, Metastatic Breast Carcinoma Trial in United States

Recruiting
  • Anatomic Stage IV Breast Cancer AJCC v8
  • +2 more
  • Los Angeles, California
  • +4 more
Jul 19, 2022

Triple Negative Breast Tumors Trial in Worldwide (alpelisib, , nab-paclitaxel)

Active, not recruiting
  • Triple Negative Breast Neoplasms
  • Los Alamitos, California
  • +154 more
Jan 12, 2023

HER2-low in Metastatic Breast Cancer Patients

Not yet recruiting
  • HER2-negative
    • (no location specified)
    Nov 9, 2023

    Metastatic Breast Cancer Trial in Spain (Ipatasertib, Trastuzumab, Pertuzumab)

    Recruiting
    • Metastatic Breast Cancer
    • Badalona, Barcelona, Spain
    • +9 more
    Oct 24, 2022

    Advanced Solid Tumor, PIK3CA Mutation, PTEN Loss of Function Mutation Trial in United States (Serabelisib, Insulin Suppressing

    Recruiting
    • Advanced Solid Tumor
    • +2 more
    • Birmingham, Alabama
    • +9 more
    May 25, 2022

    Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8

    Suspended
    • Anatomic Stage III Breast Cancer AJCC v8
    • +12 more
    • Copanlisib Hydrochloride
    • Eribulin Mesylate
    • Gainesville, Florida
    • +10 more
    Nov 16, 2022

    HER2-negative Breast Cancer, Metastatic Breast Cancer, Metaplastic Breast Carcinoma Trial in Houston (L-NMMA)

    Recruiting
    • HER2-negative Breast Cancer
    • +3 more
    • Houston, Texas
      Houston Methodist Neal Cancer Center
    Jan 12, 2023

    Advanced Malignant Solid Tumor, Locally Advanced Malignant Solid Tumor Trial (drug, procedure, biological)

    Not yet recruiting
    • Advanced Malignant Solid Neoplasm
    • Locally Advanced Malignant Solid Neoplasm
    • (no location specified)
    Dec 2, 2022

    Anatomic Stage IV Breast Cancer AJCC v8, Hormone Receptor-Positive Breast Carcinoma, Metastatic Breast Carcinoma Trial in United

    Recruiting
    • Anatomic Stage IV Breast Cancer AJCC v8
    • +4 more
    • Birmingham, Alabama
    • +12 more
    Nov 9, 2022

    Metastatic Breast Cancer Trial in United States (Orteronel)

    Completed
    Has Results
    • Metastatic Breast Cancer
    • New Haven, Connecticut
    • +9 more
    Jun 8, 2022

    Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Cancer, Invasive Ductal Breast Carcinoma Trial in Boston,

    Active, not recruiting
    • Estrogen Receptor-positive Breast Cancer
    • +5 more
    • PI3K inhibitor BYL719
    • +3 more
    • Boston, Massachusetts
    • +1 more
    Oct 14, 2022

    Metastatic Breast Cancer Trial in Taipei City, Taipei, Yuanlin (Olaparib, Chemotherapy drug)

    Recruiting
    • Metastatic Breast Cancer
    • Taipei City, Please Select, Taiwan
    • +2 more
    Nov 27, 2022

    Breast Cancer, Prostate Cancer, Advanced Solid Tumors Trial in Middletown, Harrison, New York (AZD5363, Enzalutamide,

    Active, not recruiting
    • Breast Cancer
    • +2 more
    • Middletown, New Jersey
    • +2 more
    Jul 5, 2022

    Advanced Solid Tumor, NSCLCs Trial in Houston (Adagrasib, Olaparib)

    Not yet recruiting
    • Advanced Solid Tumor
    • Non-small Cell Lung Cancers
    • Houston, Texas
      M D Anderson Cancer Center
    Nov 15, 2023

    Breast Cancer Trial in Los Angeles (Pembrolizumab, Olaparib)

    Active, not recruiting
    • Breast Cancer
    • Los Angeles, California
      Cedars-Sinai Medical Center
    Feb 1, 2023

    Lymphatic Malformations Trial (Alpelisib, Placebo)

    Not yet recruiting
    • Lymphatic Malformations
    • (no location specified)
    Jul 4, 2023